Monday Night Football betting breakdown for Week 16 of the 2025 NFL season featuring the San Francisco 49ers vs Indianapolis Colts. In this video, I share my best NFL picks, player props, and game predictions for MNF, with a special focus on Philip Rivers, Jonathan Taylor, Brock Purdy, and Christian McCaffery Player Props.
Plays:
- Philip Rivers Over 149.5 Passing Yards (0.33 units, -146 FanDuel)✅
- SGP: Colts +14, Over 36.5 (0.33 units, -137 Fanatics Boosted)❌
- SGP: Christian McCaffery Over 49.5 Rushing Yards, George Kittle Over 39.5 Receiving Yards, Jauan Jennings Over 29.5 Receiving Yards (0.33 units, +158 FanDuel Boosted)✅
💰 Sign up for *Underdog* and use code *GUYBOSTON* : https://play.underdogfantasy.com/p-guybostonsports
📊 For the ABSOLUTE BEST Sports Research Tool, check out *Outlier* : https://outlier.bet/GuyBoston
